Inflammatory diet linked to testosterone deficiency in men
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This study investigated the association between Dietary Inflammatory Index and sex hormones in a large, nationally representative adult male sample.

Researchers utilized data from the 2013–2014 and 2015–2016 National Health and Nutrition Examination Survey. Males aged more than 20 years who provided a 24-hour dietary intake history and underwent serum sex hormone testing were included in analysis. Weighted proportions and multivariable analysis controlling for age, race, energy, smoking status, education level, body mass index and time of venipuncture were used to evaluate the associations between Dietary Inflammatory Index and sex hormones.

Results:
-- For 4,151 participants, Dietary Inflammatory Index ranged from ?5.05 to 5.48.

-- Mean±SD total testosterone was 419.30±176.27 ng/dl.

-- Mean±SD total testosterone was lower among men in the highest tertile compared with men in the lowest tertile group.

-- A per unit increase in Dietary Inflammatory Index was related to 4.0% higher odds of testosterone deficiency.

-- In the fully adjusted multivariable model, males in Dietary Inflammatory Index tertile 3 (the most pro-inflammatory) had 29.6% higher odds of testosterone deficiency than those in tertile 1.

-- Interaction tests revealed no significant effect of body mass index on the association of Dietary Inflammatory Index with testosterone deficiency and all sex hormone parameters.

Conclusively, men adhering to a more pro-inflammatory diet appear to have a higher risk of testosterone deficiency, indicating the important role of diet in male reproductive health.

Source: https://www.auajournals.org/doi/10.1097/JU.0000000000001703?utm_source=press&utm_medium=press&utm_campaign=ju_diet_pr_042121
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