Inflammatory markers prognostic in primary sinonasal cancer
The researchers found that in analysis of epithelial tumors (adenocarcinoma and carcinoma) and advanced-stage tumors (pT3-T4), patients with higher NLR and PLR had shorter overall and disease-free survival. NLR and PLR were independent prognostic factors for disease-free survival, with the risk of recurrence reduced among patients with NLR <2.6 and PLR <156.9 (hazard ratios, 0.39 and 0.34, respectively).

In conclusion, this study demonstrates that systemic inflammatory serum markers at presentation may be used as predictors of mortality and recurrence for advanced-stage epithelial paranasal sinus cancers, the authors write. Future studies are needed to better understand inflammatory response mechanisms in such a rare and aggressive disease.

http://medicalxpress.com/news/2017-01-inflammatory-markers-prognostic-primary-sinonasal.html
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