Interface fluid syndrome: A potential lifelong complication
The present case has been reported in the American Journal of Ophthalmology Case Reports.

A 46-year-old male presented with eye pain and blurred vision in the right eye that he had been experiencing for 1 year. He had undergone successful LASIK operation in both eyes for a myopic refractive error 16 years earlier. The best-corrected visual acuity (BCVA) of the right eye was 20/20. He presented with eye pain and vision impairment in the right eye 6 years later and was diagnosed with PSS by unilateral, nongranulomatous, anterior uveitis accompanied by markedly elevated intraocular pressure.

The IOP of the right eye at that time was 36 mmHg by Non-contact Tonometer (NCT), and was treated with steroids and topical β-blocker eye drops. It had been well controlled within 15 days. From then on, PSS recurred almost twice per year, and was successfully treated by the same strategy each time. The bouts of PSS lengthened to nearly 3 months in the past three years.

A combination of three types of anti-glaucoma eye drops were used (topical timolol maleate 0.5% twice daily, brimonidine 0.15% thrice daily, travoprost 0.004% once at bedtime) to control the IOP, in addition to steroids to treat the PSS. During these outbreaks, IFS was never found by slit-lamp examination or anterior segment OCT. The PSS ultimately reacted positively to the treatments every time. While, he presented with vision decline one year ago with a diagnosis of PSS, the IOP of the right eye was 20 mmHg.

The IOPs of the right eye were from 22 to 45 mmHg during the past year, and edema of the cornea began. OCT examination only showed a thickening of the cornea (Fig. 1). However, the visual acuity of right eye dropped drastically to 4/200 on December 27, 2016. IFS was suspected and confirmed using high-resolution OCT. Edema of the entire cornea was observed, and every layer was involved (Fig. 2A). The clear space here was showed by OCT (Fig. 3A). In consideration of the uncontrollable IOP and formation of the IFS, a trabeculectomy was performed on December 30, 2016.

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