Intracranial lesion as onset symptom in a patient with early
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The term undifferentiated connective tissue disease (UCTD) refers to unclassifiable systemic autoimmune diseases, which share some clinical and serological manifestations with definite connective tissue diseases (CTDs) but not fulfilling any of the existing classification criteria for certain CTDs, such as systemic lupus erythematosus (SLE), systemic sclerosis (SSc), Sjögren syndrome (SS), dermatomyositis/polymyositis (DM/PM), mixed connective tissue diseases (MCTD) and rheumatoid arthritis (RA). It is now widely accepted that UCTD represent a distinct clinical entity including two subgroups: stable UCTD and early UCTD. Among these UCTD patients, severe organ involvements (such as heart, renal or neurological manifestations) are rarely reported. Here, we firstly described a female early UCTD patient with intracranial lesions as the onset and main clinical manifestations in order to improve the diagnosis and treatment of the disease.......

https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-017-0868-4
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