Intrahepatic Cholestasis of Pregnancy Leading to Severe Vita
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Obstetric hemorrhage is the leading direct cause of both maternal mortality and near-miss events.Intrahepatic cholestasis of pregnancy is seldom associated with significant vitamin K deficiency and severe coagulopathy. Usually, nutritional deficiencies, medication usage, and liver disease lead to this disorder.The fetus and the newborn are dependent on maternally derived vitamin K facilitated diffusion transport across the placenta for coagulation stability as well. We report a patient presenting with pruritus, preterm labor, and hematuria, finally diagnosed with intrahepatic cholestasis of pregnancy (ICP) complicated with pathologic vitamin K deficiency....

https://www.hindawi.com/journals/criog/2017/5646247/
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