Invasive Group B Streptococcal Disease in Two Pediatric Pati
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Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease which can cause severe acute and chronic multiorgan damage and death. Treatment with corticosteroids and other immune-suppressive drugs has improved the 5-year-survival rate of SLE from 50% in the mid-fifties to over 90% in the last decade. However, this treatment is still associated with serious complications, including severe infections. Invasive secondary infections can be responsible for approximately 25% of SLE related deaths.We report two patients with SLE who were treated with steroids and immunosuppressive medication and then developed invasive Group B Streptococcus (GBS) infections....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638523/
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