Is Sleep Apnoea An Independent Risk Factor For Severe COVID-
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Obstructive sleep apnoea (OSA) is associated with higher body mass index (BMI), diabetes, older age and male gender, which are all risk factors for severe COVID-19. Researchers demonstrated the higher risk for COVID-19 hospitalisation in patients with OSA, independently of BMI and other known risk factors for OSA.

Researchers aimed at evaluating if OSA associates with the risk for severe COVID-19 infection independently of other potential risk factors including age, sex, body mass index (BMI), hypertension, diabetes, coronary heart disease (CHD) asthma and chronic obstructive pulmonary disease (COPD), and also whether the risk for contracting COVID-19 is elevated among patients with OSA.

Key findings of the study are:

1. Of all patients with COVID-19 diagnosis; 38 patients also had OSA diagnosis.

2. Among Severe COVID-19, OSA occurred in 19 patients.

3. Prevalence of OSA , hypertension, diabetes ,obesity and CHD were statistically significantly higher in the hospitalised group.

4. Patients with OSA had the same risk of contracting COVID-19 than non-OSA individuals, but patients with OSA had a considerably elevated risk for being hospitalised due to severe COVID-19.

There are at least two potential pathological mechanisms how OSA may relate to severe COVID-19. First, individuals with OSA often have one or more comorbidities that are known risk factors for severe COVID-19. For example, high BMI increases the risk for severe COVID-19. Furthermore, OSA exacerbates the effects of many underlying risk factors increasing blood pressure.

Second, OSA may worsen the core symptoms of severe COVID-19, especially during the night, when decreased oxygen saturation levels occur in OSA. The findings of current study together with earlier reports suggest that OSA should be taken into account when assessing who will develop life-threatening complications of COVID-19 infection.

Authors conclude: "Patients with OSA had 2.93 times higher risk to be hospitalised when affected by COVID-19 than
non-OSA individuals."

Dr. T●●●●z H●●●●●●i and 3 others like this