Keto Versus Mediterranean Diet: Which Is Better for Diabetes
This study compared 2 low-carbohydrate diets with 3 key similarities and 3 key differences for their effects on glucose control and cardiometabolic risk factors in individuals with prediabetes and T2DM. The primary analysis was of 33 participants with complete data. The HbA1c values did not differ between diets at 12 weeks. Triglycerides decreased more for the well-formulated ketogenic diet (WFKD) and LDL cholesterol was higher for the WFKD. Weight decreased 8% compared with 7% and HDL cholesterol increased 11% compared with 7% for the WFKD compared with the Mediterranean-plus diet (Med-Plus), respectively; however, there was a significant interaction of diet x order for both. Participants had lower intakes of fiber and 3 nutrients on the WFKD compared with the Med-Plus. Twelve-week follow-up data suggest the Med-Plus is more sustainable. Therefore, both the ketogenic and Mediterranean diets successfully cut blood sugar levels in patients with prediabetes or type 2 diabetes.