Labyrinthine Ossificans
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Labyrinthine ossificans (LO) is a condition in which the normal membranous labyrinth becomes replaced by fibrous and/or osseous tissue. A three-stage classification has been proposed for labyrinthitis: acute inflammatory, fibroblastic, and eventual osseous formation. LO consists of the fibrous and osseous stages. Spread of intracranial infection to the membranous labyrinth is the most common etiology of labyrinthitis/LO, with other routes of infection including contiguous spread from the auditory canal and hematogenous. Less common etiologies include trauma, tumor, prior surgery, vascular, inflammatory, and hematologic disorders. When LO is associated with bacterial meningitis, bilateral inner ear involvement is common.Patients most often present with sensorineural hearing loss of the affected side.A 6-year-old girl presented with a 3- to 6-month history of sensorineural hearing loss.

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