Link discovered between the number of antibiotic prescriptio
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Previous research reported that individuals prescribed antibiotics frequently develop antimicrobial resistance. An association between the number of prescriptions for antibiotics and a higher risk of hospital admissions have been discovered by the epidemiologists at The University of Manchester as per a study published in BMC Medicine.

A total of 1.8 million patients with repeated antibiotic use were included in the study. Patients who had 2 antibiotic prescriptions were 1.23 times more likely, patients who had 3 to 4 prescriptions 1.33 times more likely and patients who had 5 to 8 1.77 times more likely to go to the hospital with another infection in three or more months.

The patient records, from 2000 to 2016, covered common infections such as upper respiratory tract, urinary tract, ear, and chest infections and excluded long term conditions such as cystic fibrosis and chronic lung disease. The risks of going to the hospital with another infection were related to the number of antibiotic prescriptions in the previous three years.

Repeated courses of antibiotics, although common practice, may have limited benefits and indicators of adverse outcomes. A potential mechanism is that antibiotics may cause dysbiosis (perturbations of intestinal microbiota), contributing to colonization with resistant bacteria. Antibiotics should be used judiciously and only periodically unless indicated.

Source: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-020-1504-5
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