Long-term experience of local vancomycin use in low post-art
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
The use of intrawound vancomycin powder in TKA surgery has shown very disparate results. Furthermore, although the CDC guidelines are generally effective, they are not explicitly designed for post-TKA infections. The authors present a 7-year experience with vancomycin in primary TKA at a high-volume tertiary knee core. In addition, new requirements for identifying suspected superficial post-TKA infections are suggested.

This is a retrospective analysis of primary total knee arthroplasties performed in a tertiary knee center. All patients with follow-up periods of less than 1 year were excluded from the study. Since March 2011, all patients received vancomycin (powder, 1 g) before water-tight closure of the joint capsule. A comparison was made between this group and historical control subjects. Altogether, 2024 patients were included in the study.

Results:
--The vancomycin and the control groups included 1710 and 314 cases respectively.
--Patients were mostly women (male to female ratio, 1 to 4), with a mean age of 65.20 (SD = 10.83) years.
--In the vancomycin group, the rate of suspected SII (1.87%) and PJI (0.41%) was significantly lower than the control group.

In conclusion, this experience suggests that using local vancomycin during TKA surgery may be a fair infection prevention measure.

Source: https://josr-online.biomedcentral.com/articles/10.1186/s13018-021-02344-2
Like
Comment
Share