Long-term outcome after superficial keratectomy of the abnor
A Study to investigate the etiology and long-term surgical prognosis of the abnormal epithelium for partial limbal stem cell deficiency (LSCD), following superficial keratectomy.

This single-center, retrospective study was conducted to assess the prognosis of consecutive patients who underwent superficial keratectomy, with or without amniotic membrane transplantation (AMT), for the treatment of partial LSCD. Researchers analyzed the etiologies of partial LSCD, surgical success rate, prognosis for recurrent cases, and the improvement in visual acuity.

--40 patients with partial LSCD were included . All eyes were in clinical stage II without dense fibrovascular tissue.

--Idiopathy was the most common etiology, followed by multiple surgeries involving the limbus (19%). All eyes attained corneal re-epithelialization and transparency.

--Furthermore, the visual acuity improved or remained unchanged postoperatively.

--Researchers observed recurrence in 19 eyes (37%) with a mean follow-up period of 26.3 months.

--Despite no significant difference in the recurrence rates among different etiologies, postoperative delayed epithelialization and extensive limbal involvement were identified as risk factors for recurrence.

--Repeat surgeries were performed in 16 eyes. The final success rate was 84%.

Of conclusion, superficial keratectomy is useful for the therapy in the postoperative visual acuity of partial LSCD in a wide range of etiologies. While the surgery may be repeated and has a high success rate, in the long postoperative course there have been several recurrences.

Source: https://www.sciencedirect.com/science/article/abs/pii/S0002939421003160?dgcid=rss_sd_all