Longevity Without Alzheimer's Tied to Lifestyle
Researchers evaluated data from 2,449 older adults with a mean age of 76 in the Chicago Health and Aging Project (CHAP) who were recruited from 1993 to 2009. The study population included 2,110 people free of Alzheimer's dementia at baseline and 339 people with prevalent Alzheimer's dementia. More than half of participants (57% of women and 56% of men) were Black or African American.

Participants completed detailed food frequency and lifestyle questionnaires. A healthy lifestyle score was based on five factors: a diet rich in whole grains, green leafy vegetables and berries and low in fast food, fried food, and red meats; late-life cognitive activities like reading, playing games, or visiting a museum; at least 150 minutes a week of moderate or vigorous physical activity including walking for exercise, gardening, or swimming; not smoking; and low-to-moderate alcohol consumption.

Diet quality was determined using the Mediterranean-DASH Diet Intervention for Neurodegenerative Delay (MIND) diet score, which has been significantly associated with a slower cognitive decline and lower risk of incident Alzheimer's dementia.

For each lifestyle factor, participants received a score of 1 if they met criteria for healthy and 0 if they did not. Scores from five lifestyle factors were summed to yield a final score ranging 0 to 5, with a higher score indicating a healthier lifestyle.

People who had four or five healthy lifestyle factors -- spanning diet, cognitive activity, physical exercise, smoking, and alcohol patterns -- at age 65 lived longer than their counterparts with zero or one healthy factors. Women added 3.1 years of life, while men added 5.7 years. Of their total life expectancy at age 65, women with four or five healthy factors spent 10.8% of their remaining years with Alzheimer's dementia, while women with zero or one factors spent 19.3%. Men with four or five healthy factors spent 6.1% of their remaining life with dementia, while those with zero or one spent 12%. A healthy lifestyle was tied to a longer life but the extra years did not mean more time living with Alzheimer's dementia.

Source: https://www.medpagetoday.com/neurology/alzheimersdisease/98199https://www.medpagetoday.com/neurology/alzheimersdisease/98199