Low-Cost Intervention keeps Tiny Newborns Alive
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Immediate "kangaroo mother care" for infants born with low birth weight led to a substantially lower risk of early death, researchers reported.

Researchers conducted a randomized, controlled trial involving infants with a birth weight between 1.0 and 1.799 kg who were assigned to receive immediate kangaroo mother care (intervention) or conventional care in an incubator or a radiant warmer until their condition stabilized and kangaroo mother care thereafter (control).

The primary outcomes were death in the neonatal period (the first 28 days of life) and in the first 72 hours of life. A total of 3211 infants and their mothers were randomly assigned to the intervention group (1609 infants with their mothers) or the control group (1602 infants with their mothers). The median daily duration of skin-to-skin contact in the neonatal intensive care unit was 16.9 hours in the intervention group and 1.5 hours in the control group.

--Neonatal death occurred in the first 28 days in 191 infants in the intervention group and in 249 infants in the control group; neonatal death in the first 72 hours of life occurred in 74 infants in the intervention group and in 92 infants in the control group.

--The trial was stopped early on the recommendation of the data and safety monitoring board owing to the finding of reduced mortality among infants receiving immediate kangaroo mother care.

Among infants with a birth weight between 1.0 and 1.799 kg, those who received immediate kangaroo mother care had lower mortality at 28 days than those who received conventional care with kangaroo mother care initiated after stabilization; the between-group difference favoring immediate kangaroo mother care at 72 hours was not significant.

New England Journal of Medicine
Source: https://www.nejm.org/doi/full/10.1056/NEJMoa2026486
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