Researchers hypothesis inferrred that lung function may recover in children in the months following an asthma exacerbation.
A dataset was used of children with asthma where lung function (including FEV1, FEV1/FVC ratio and FEF25-75) was measured at 3 month intervals over a year. Mixed level models compared spirometry measured on two occasions three-months apart before a single exacerbation (assessments 1 and 2) to measurements made on two occasions after the exacerbation (assessments 3 and 4), with adjustment for covariates. Changes in spirometry over a year were also analysed across those with exacerbations in no, one or more than one three month periods.
--For the 113 children who had a single exacerbation, spirometry measured made at assessment 1 or 2 did not differ at assessments 3 or 4 when the whole population was considered.
--When categorised into tertiles by change in