Lymphoepithelial carcinoma of the larynx
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Lymphoepithelial carcinoma of the larynx accounts only for 0.2% of all laryngeal cancers.The relationship between Epstein–Barr virus (EBV) and laryngeal lymphoepithelial carcinoma remains controversial.Herein, we describe a case of 81-year-old male, with a chronic smoking history, presented with complaint of dysphonia over one year period. The evolution was marked by the occurrence of dysphagia and severe dyspnea requiring emergency tracheostomy. Computed tomography scan of the neck showed a mass involving the entire larynx associated to cervical adenopathies. Endoscopic examination confirmed the findings of an ulcerated lesion affecting the three parts of the larynx and extending to the base of the tongue as well as to the postcricoid region. A biopsy of the lesion has been performed. Histological examination and immunohistochemistry revealed lymphoepithelial carcinoma of the larynx. Screening for Epstein–Barr virus (EBV) by immunohistochemical examination was negative. As the tumor was considered inoperable, the patient was treated solely with radiation therapy....

http://www.edoriumjournals.com/journal-of-case-reports-and-images-in-oncology/archive/2017-archive/100033Z10KA2017-asmaa/100033Z10KA2017-asmaa-full-text.php
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