MASC Presenting as a Cervical Lymph Node Metastasis of Unkno
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Mammary analogue secretory carcinoma (MASC) is a pathological entity arising in the salivary glands first described by Skalova et al. Here, we report the ?rst case of MASC presenting as a cervical lymph node metastasis of unknown primary site together with a brief review of the literature. We present a 74-year-old male with a painless lump in his left neck. Based on the fine-needle aspiration cytological findings, a possible malignant tumor was suspected. No evidence of a primary lesion was observed using imaging modalities including positron emission tomography/computed tomography. The patient underwent an ipsilateral modified radical neck dissection. Immunohistochemical staining showed that the neoplastic cells were positive for S100 protein and GATA3. A rearrangement of the ETV6 gene was noted during ?uorescence in situ hybridization, and the final histopathological diagnosis was MASC....

https://www.karger.com/Article/FullText/457949
Like
Comment
Share