Curcumin, a compound found in turmeric, has anti-inflammatory and antioxidant properties and is known to suppress angiogenesis in malignant tumors. Bioengineers have now discovered that when delivered through magnetic hydrogels into stem cell cultures this versatile compound paradoxically also promotes the secretion of vascular endothelial growth factor, or VEGF, that helps vascular tissues grow.
This finding could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients.
Source: Radha Daya, Changlu Xu, Nhu-Y. Thi Nguyen, Huinan Hannah Liu. Angiogenic Hyaluronic Acid Hydrogels with Curcumin-Coated Magnetic Nanoparticles for Tissue Repair. ACS Applied Materials & Interfaces, 2022; 14 (9): 11051 DOI: 10.1021/acsami.1c19889