Maternal anaphylactic shock in pregnancy: A case report
Anaphylaxis is a very rare event in pregnancy, triggering maternal hypotension leading to intrapartum hypoxic-ischemic encephalopathy in infant. Furthermore, cesarean sections are performed at a high rate in anaphylactic pregnant women.

The present case has been published in the journal Medicine. A 34-year-old pregnant woman presented with maternal anaphylaxis following prophylactic antibiotic injection for cesarean section. Within a few minutes after initiation of intradermal skin test with cefotetan, the pregnant woman developed generalized itchy rash, chest tightness, and dyspnea.

Several minutes after the injection of antibiotics, a diffuse urticarial rash was detected over her face and trunk followed by complaints of chest tightness and dyspnea. She was diagnosed with hypotension and hypoxia. Further, fetal heart tones showed bradycardia. A presumptive diagnosis of anaphylactic reaction induced by cefotetan was made for surgical prophylaxis.

The patient was managed for anaphylaxis, via administration of epinephrine, glucocorticoid, and antihistamine. Emergency cesarean section performed under general anesthesia resulted in a favorable perinatal outcome for the fetus. Maternal and fetal outcomes were good after prompt treatment for anaphylaxis and emergency cesarean section.

Key takeaways:-
• This is the first reported case of anaphylaxis following cefotetan administration in pregnancy. Cefotetan, a second-generation cephalosporin, is a commonly prescribed antibiotic used to treat a wide range of bacterial infections.

• The case demonstrated a life-threatening anaphylactic reaction during pregnancy. Even a skin test using antibiotics alone triggered anaphylaxis.

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Dr. R●●●t B●●●●l and 47 others like this13 shares
Dr. H●●●●h D●●●i
Dr. H●●●●h D●●●i Obstetrics and Gynaecology
No antibiotics - old or new and no IV injections should be taken lightly.
Sep 24, 2018Like3
Dr. L●●●●●●●●u S●●h
Dr. L●●●●●●●●u S●●h Obstetrics and Gynaecology
No prediction can be given about any drugs!! Anaphylaxis is as dangerous as shock!!One cannot be present to tide over such events!!
Sep 28, 2018Like