Maternal and neonatal outcomes in women undergoing Roux-en-Y
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Roux-en-Y gastric bypass surgery lowers the risks of preterm premature rupture of membranes and large for gestational age/ macrosomia, finds a study published in the European Journal Obstetrics & Gynecology and Reproductive Biology.

The aim was to summarize evidence of benefits and risks of maternal and neonatal outcomes among pregnant women after Roux-en-Y gastric bypass surgery.

A systematic search was conducted in MEDLINE, EMBASE, Web of Science, Ovid, and Cochrane Library. Inclusion criteria were randomized trials or observational studies including at least one of maternal or neonatal outcomes from pregnant women who had a history of Roux-en-Y gastric bypass surgery with a control group of pregnant women with no history of bariatric surgery. Nine retrospective articles were eligible including 10 273 pregnant women with a history of Roux-en-Y gastric bypass surgery and 222 789 pregnant women without a history of bariatric surgery.

- The meta-analysis results showed a lower incidence of preterm premature rupture of membranes, large gestational age infants, or macrosomia in women after Roux-en-Y gastric bypass surgery.

- On the other hand, infants born to mothers with a history of Roux-en-Y gastric bypass surgery had an increased risk of small gestational age.

Conclusively, Roux-en-Y gastric bypass surgery reduces risks of preterm premature rupture of membranes and large for gestational age/ macrosomia but increases the risk of small for gestational age.

European Journal Obstetrics & Gynecology and Reproductive Biology
Source: https://doi.org/10.1016/j.ejogrb.2021.07.006
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