Mature bony metaplasia in multinodular goiter: A case report
Various degenerative changes can be seen in multinodular goiter. These include cystic changes, hemorrhage, fibrosis and calcification. However, osseous metaplasia is extremely rare.

A 44-year-old lady with multiple ill-defined thyroid nodules upon physical examination. Thyroid ultrasound showed multiple variably sized nodules with cystic degeneration. The largest left lobe nodule showed macrocalcification. Further evaluation was advised by the radiologist. Total thyroidectomy was performed and it revealed histological osseous metaplasia with lamellar bone formation. The clinical course following resection was unremarkable.

Source: International Journal of Surgery case reports

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