Medical expulsive therapy or bust?
Whether or not medical expulsive therapy (MET) is a sound recommendation for patients with kidney or ureteral stones is a matter of debate. MET still has a role in the management of some patients, according to AUA guidelines for the management of ureteral calculi. But a large, multicenter study in The Lancet (2015; 386:341–9) found no evidence supporting the use of MET with the alpha-blocker tamsulosin or the calcium channel blocker nifedipine. The lead author of that study told Urology Times that, based on the results, these drugs should no longer be recommended or used to reduce the risk of intervention required to remove stones in people with ureteric colic.