Melatonin Supplements Improve Objective Sleep Quality In Ins
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A recent study published in the journal Sleep Medicine suggests Melatonin supplementation over a four-week period is effective and safe in improving some aspects of objective sleep quality.

Researchers recruited 97 middle-aged patients with primary insomnia, they were randomly assigned to receive either 3 mg fast-release melatonin or placebo for four-weeks. They tested the objective sleep parameters by overnight polysomnography.

Subjective sleep performance and daytime somnolence obtained from the Pittsburgh Sleep Quality Index (PSQI). Insomnia Severity Index (ISI) and Epworth Sleepiness Scale (ESS) were obtained at baseline and after treatment. Patients underwent treatment daily 1 h before bedtime.

The team found melatonin supplementation significantly decreased early wake time and percentage of N2 sleep. However, they found no significant effect on other objective sleep parameters including sleep latency, sleep efficiency, wake during the sleep and percent of N1, N3 and REM sleep. They observed no effect of melatonin on insomnia symptoms and severity on the PSQI, ISI and ESS and didn't report any adverse event.

It was concluded that, Melatonin supplementation over a four-week period is effective and safe in improving some aspects of objective sleep quality such as total sleep time, percentage of rapid eye movement and early morning wake time in middle-aged patients with insomnia.

Source:
https://www.sciencedirect.com/science/article/abs/pii/S1389945720304743?via=ihub
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