Metastatic Lung Adenocarcinoma to the Appendix
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There are few reported cases in the literature of metastasis to the appendix. A 44-year-old patient presented with abdominal pain and changes in the bowel pattern. Thoracic and abdominal computed tomography scans evidenced pulmonary and liver nodules. The pulmonary nodule was biopsied and the hematoxylin-and-eosin (HE) stained slides showed an adenocarcinoma. The immunohistochemistry profile demonstrated positivity for CK7 and TTF-1. The patient underwent an appendectomy. HE stained slides also demonstrated adenocarcinoma infiltrating the entire appendix wall along with the epithelial surface with immunohistochemistry study of the appendix neoplasm showing exactly the same results as seen in the first panel.

Case Report

Male patient, 44, smoker, 25 years/pack, having stopped 5 years in outpatient treatment with Clexane® due to prior deep vein thrombosis. Complained of abdominal pain and changes in bowel habits there is four months. Initially it was treated with symptomatic drugs, but without improvement. Showed increased abdominal volume being admitted to another institution for diagnostic investigation. Began the research with colonoscopy that showed one substenosis in the colon, at the level of the splenic flexure, preventing the progression of the device, without changes in the colonic mucosa. It underwent computed tomography (C) of the chest and abdomen which revealed bilateral pulmonary nodules, the largest in the right upper lobe, spiculated, measuring 2.7 cm in major axis and multiple secondary aspect of liver damage with peritoneal implants....