Metastatic bladder cancer with lesion to the proximal femur
Published in the journal Case Reports in Orthopaedics, the authors present a case of muscle-invasive bladder cancer with metastasis to the proximal femur treated with intramedullary stabilization, in which intramedullary reaming were inconclusive for pathology and an open biopsy was required.

Although the most common primary tumors with metastasis to bone are prostate, breast, kidney, lung, and thyroid cancer; metastasis to bone occurs in 30–40% of patients with muscle-invasive bladder cancer. The femur is the third most common location for bladder cancer metastasis to bone surpassed by the spine and pelvis.

A 72-year-old male with a long smoking history presented to the urology clinic secondary to episodes of gross hematuria. He was diagnosed with bladder cancer and underwent a transurethral resection of bladder tumors, which revealed invasive high-grade urothelial (transitional) cell carcinoma (T2N0M0). He was treated with four cycles of neoadjuvant gemcitabine and carboplatin followed by a radical cystectomy with ileoconduit.

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