Methyldopa Hepatotoxicity: A Paradoxical High-Risk Pregnancy
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Alpha methyldopa is one of the preferred medications for hypertension control in pregnant women because of its low teratogenic profile. However, when pregnant women on this medication develop an acute or chronic liver damage, methyldopa is not thought to be responsible. At 18 weeks gestation of a high-risk pregnancy, a patient with chronic hypertension controlled on methyldopa 500 mg three times daily, presented with jaundice, dark-colored urine and elevated liver function enzymes.This case report highlights the fact that adverse drug reactions to methyldopa are still occurring and chronic complications which could have been avoided arise....

http://www.jcgo.org/index.php/jcgo/article/view/343/197
Dr. H●●●●h D●●●i and 6 others like this
Like
Comment
Share