Microfluidic Test for Viral Antibodies Takes Just 20 Minutes
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Researchers at Hokkaido University in Japan have developed a microfluidic test that can detect antibodies against viral infection.

• The device can provide a result in as little as 20 minutes and requires only 2 microliters of serum to run.

• Existing techniques rely on a visual assessment to determine whether a result is positive. This means that the accuracy is limited, as interpreting results is subject to human error.

• To address this, these researchers have developed a new type of microfluidic test, which is based on binding a fluorescently labeled protein to the antibody of interest in a serum sample.

• The technique involves detecting the fluorescence polarization of the bound fluorescent molecules, and liquid crystal molecules are used to control the direction of this polarization.

• Once the sample is within the microfluidic device, the fluorescence polarization analyzer measures the fluorescence signal and indicates if the antibody is present in the sample.

• The entire process takes only 20 minutes, and such devices could help to speed up and streamline community testing for antibodies related to COVID-19 and allow for testing outside of medical labs.

https://www.medgadget.com/2020/05/microfluidic-test-for-viral-antibodies-takes-just-20-minutes.html
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