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Biopsy-proven iris melanomas have been found to carry a 10.7% risk for metastasis. Thus a safe method of iris tumor biopsy is needed. Anterior uveal tumors are accessible for biopsy, cytologic, histopathologic molecular and genetic evaluation. Specimens can be obtained by fine-needle aspiration biopsy, wide-incision surgical iridectomy, or aspiration cutter techniques.Herein, we describe a technique for minimally invasive, multifocal, aspiration cutter-assisted iris biopsy. This is a variation of the Finger iridectomy technique (FIT) that has been shown to offer cells for cytology (like fine-needle aspiration biopsy) as well as small pieces that can be evaluated by histopathology and immunohistochemistry.
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