Mild encephalitis with a reversible splenial lesion due to r
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Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinico-radiological entity, which is characterized by transient abnormalities in the splenium of the corpus callosum (SCC) associated with mild central nervous system (CNS) symptoms. MERS is often described in children, unlike in adults, which is rare. Its etiologies are variable, dominated by infectious causes. Its reversibility and favorable prognosis make all the particularity of this syndrome. A 27 years old man, with no previous particular medical history, was received in our department with seven days psycho-behavioral instability. He presented with incoherent conversations, mystical delusion, spatial disorientation associated with fever (38°C) and cold-like symptoms during this episode. The neurological examination did not show either the sensorimotor deficit or meningeal signs. Encephalic Magnetic Resonance Imaging has revealed an abnormality in the SCC: hyperintense on T2-weighted images, fluid-attenuated inversion recovery images, and diffusion weighted images with decreased apparent diffusion coefficient values; isointense on T1-weighted imaging without enhancement after gadolinium injection.

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