Mucoepidermoid carcinoma presenting as ranula: a case report
Malignant tumors of the salivary gland are rare, clinically diverse group of neoplasms, among which mucoepidermoid carcinomas (MECs) are reported to be most frequently occurring epithelial carcinomas. MEC at times misleads the clinician because of its atypical location and innocent appearance. The present case has been reported in the Journal of Cancer Therapeutics and Research.

A 70-year-old female patient came with a chief complaint of swelling on the left side of floor of the mouth for 1 year, which was associated with mild pain for 1 month. The patient noticed a small swelling in floor of the mouth, which was initially smaller and gradually increased to the present size.

Intraoral soft tissue examination revealed a solitary diffuse swelling seen on floor of the mouth on left side which is roughly oval and measuring about 2 cm × 3 cm extending anteriorly from lingual frenum and posteriorly till mesial aspect of 36, medially ventral aspect of tongue, and laterally extending into lingual vestibule in relation to 32–36.


Surface color of the swelling appeared to be same as that of normal mucosa with bluish tinge on the lateral aspect of swelling. On palpation, swelling was slightly tender and consistency was variable with cystic consistency at the center and hard at the periphery. Based on the history and clinical examination, it was provisionally diagnosed as ranula.

Gross specimen of excisional biopsy performed under local anesthesia, subjected to histopathological evaluation. Based on the histological features, a diagnosis of low-grade MEC was made. Adjuvant therapy of surgical excision of palpable left submandibular lymph node was offered. Follow-up of 2 years did not show any recurrence.

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