Multiparametric 3T MRI evaluation of hereditary spastic para
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Hereditary spastic paraplegia (HSP) is a heterogeneous group of familial neurodegenerative disorders characterised by progressive lower limb spasticity. Clinically, they are classified as “pure” and “complicated” when other major clinical features are present.Genetically autosomal dominant, autosomal recessive, and X-linked recessive forms of inheritance are seen. Diagnosis is principally done by the clinical criteria proposed by Harding in 1984. The genetic analysis serves as the confirmatory test. Magnetic resonance imaging of the neuraxis can help in early diagnosis and to exclude secondary causes of spastic paraplegia. We present here two cases of HSP in a single family with typical imaging findings.

https://goo.gl/KG9bPw
Like
Comment
Share