Mx in chordoid glioma: Avoiding the pitfalls in this challen
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The origin of Chordoid glioma(CG) remains unclear. Electron microscopy suggests a glial origin, specifically from cells named tanycytes. These ependymal cells are located in the anterior region of the third ventricle, around the organum vasculosum and the subforniceal organ. Chordoid glioma has a broad radiological and histological differential diagnosis. The radiological study is crucial for the diagnostic and surgical planning. The pathological confirmation of the glial nature of the chordoid glioma is mandatory, and for this, an adequate immunohistochemical panel is required. In the case of symptomatic recurrence, the conduction of a second surgery merits a careful consideration because it entails a life-threatening risk for the patient. Neither recurrence nor progression has been described in any of the cases where radiosurgery was administered after a partial resection or a biopsy. Radiosurgery might be a safe alternative to surgery with a more reasonable morbidity rate.In the management of this pathology, minimally invasive surgery might be a better initial approach. The sub-frontal supraorbital approach offers a safe route and provides an adequate exposure of the tumor and could be considered as an optimal approach to the lesion located in the anterior third ventricle.

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