Myeloid Sarcoma in an Eyelid post Chemotherapy for Acute Mye
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Myeloid sarcoma is a rare extramedullary manifestation of leukemia that consists of immature cells of the granulocytic series. Although myeloid sarcoma can involve any ocular tissue, a myeloid sarcoma in the eyelid is less common. Ocular myeloid sarcomas may appear at any time during the course of acute myeloid leukemia, and they often develop simultaneously with acute myeloid leukemia during onset or relapse. In contrast, an ocular myeloid sarcoma that develops during chemotherapy is extremely rare, with only one reported case with an intraocular lesion.

In this case report, we present a case of a myeloid sarcoma in the upper eyelid that developed during chemotherapy for acute myeloid leukemia.

Case Report
An 80-year-old female was diagnosed with myelodysplastic syndrome 1 year before referral to our clinic. She underwent erythrocyte transfusion therapy for severe anemia. As the myelodysplastic syndrome progressed to acute myeloid leukemia 3 months after the initial diagnosis, she was administered two cycles of low-dose cytarabine (20 mg/m2/day) and aclarubicin hydrochloride (14 mg/m2/day) chemotherapy, followed by azacitidine injections (1 cycle, 75 mg/m2/day × 7 days). As the patient showed a hypocellular marrow, cytarabine and aclarubicin hydrochloride were administered for 5 (recommended medication days, 14 days) and 3 days (recommended medication days, 4 days), respectively, in each cycle of the chemotherapy for preventing a delayed recovery of a normal blood count after the chemotherapy.