Neoadjuvant Chemotherapy during Pregnancy in Cervical Cancer
Current recommendations for pregnant women with cervical cancer depend on several factors, such as the stage of the disease, the gestational age at the time of diagnosis, and the patient's desire to maintain the pregnancy. A 24 weeks pregnant woman with stage IB2 cervical cancer was successfully treated with three cycles of platinum-based neoadjuvant chemotherapy followed by a simultaneous ?aesarean section and radical hysterectomy. Her newborn daughter was completely healthy at birth. This was the first case of cervical cancer during pregnancy to be treated with this approach. In the absence of clear guidelines, these patients should be treated after a decision by a multidisciplinary cancer committee, including a gynecologist-oncologist, obstetrician, pathologist, and neonatologist, to determine the best treatment option.