Nephrotic Syndrome in a Child Suffering from Tetralogy of Fa
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Introduction
Glomerular dysfunction can be found in cyanotic congenital heart disease (CHD) especially in older children and adults, being associated occasionally with proteinuria and microalbuminuria [1, 2]. The risk of developing renal impairment is particularly high in cyanotic patients particularly in patients with long-standing cyanotic CHD [1, 2]. However, nephrotic syndrome (NS) is an uncommon complication of cyanotic congenital heart disease and is rarely reported. This complication has not been documented in Congolese children.
Case Report
A 4-year-old girl with edema, dyspnea, and cyanosis was referred from Butembo at the East of the Democratic Republic of Congo (DRC) to a facility renal and cardiology investigations in Department of Pediatrics of University Hospital of Kinshasa, Kinshasa, DRC. The history of present illness dates back to about 13 months characterized by progressive cough, dyspnea, and orthopnea. Physical examination revealed respiratory distress with edema and episodes of squatting. She was cyanosed with finger and toes clubbing. Apex beat was at the fifth intercostal space anterior axillary line. Both heart sounds were noted with a systolic thrill and loud systolic ejection murmur grade 3. The blood pressure was 150/110?mmHg, and oximetry was 63%....

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548070/?report=reader
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