Neurodevelopment and growth have a bidirectional relationshi
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The aim of the research is to describe the bidirectional associations between term-born infants neurodevelopment in five domains and physical growth in early life using a cross-lagged model and data from the Born in Shenyang Cohort Study.

Research provided 688 mother-child dyads for this study. At the ages of 6 and 12 months, infant's anthropometric (weight and length) and neurological development (Gesell Development Scale) were measured. The longitudinal relationships in both directions were investigated using cross-lagged analyses and multiple linear regression analyses.

Results:
--In terms of longitudinal studies, the inverse associations between infants two skills (gross motor and social behavior) at the age of 6 months with BMI Z -scores at the age of 12 months (gross motor: abeta= -0.20; social behavior: abeta= -0.23) were found.

--Conversely, a higher infant Z -scored BMI at the age of 6 months predicted a lower gross motor at the age of 12 months (abeta= -0.08).

--In cross-lagged analyses, an adverse association in both directions between gross motor and Z -scored BMI was observed.

Finally, bidirectional relationships between infant's neurodevelopment of gross motor skills and physical growth were discovered, implying that term-born infants on the verge of developmental danger should not be ignored.

Source: https://bmcpediatr.biomedcentral.com/articles/10.1186/s12887-021-02655-7
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