Neuromyelitis optica spectrum disorder presenting as Brown-S
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Brown - Sequard syndrome (BSS) presents with features of ipsilateral motor function loss and contralateral loss of pain and temperature. It is most commonly caused by trauma/stab injuries and is also known to be caused by multiple sclerosis. Here, we are presenting a rare case of neuromyelitis optica spectrum disorder (NMOSD) presenting as Brown - Sequard syndrome.A 70-year-old female presented the emergency room with a 2–3 day history of abrupt onset weakness in her left leg. Magnetic resonance imaging (MRI) scan of the spine showed T2 hyperintense signal seen within the upper thoracic cord centered at T2–T5 level with the mild expansion of the cord. A diagnosis of neuromyelitis optica (NMO) spectrum disorder was made based on positive AQP4 antibody titres.

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