Neuromyelitis optica spectrum disorder presenting as Brown-S
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Brown - Sequard syndrome (BSS) presents with features of ipsilateral motor function loss and contralateral loss of pain and temperature. It is most commonly caused from trauma/stab injuries and is also known to be be caused by multiple sclerosis. This article presents a rare case of neuromyelitis optica spectrum disorder (NMOSD) presenting as Brown - Sequard syndrome.

Case Report: A 70-year-old female presented the emergency room with a 2–3 day history of abrupt onset weakness in her left leg. Magnetic resonance imaging (MRI) scan of the spine showed T2 hyperintense signal seen within the upper thoracic cord centered at T2–T5 level with mild expansion of the cord. A diagnosis of neuromyelitis optica (NMO) spectrum disorder was made based on positive AQP4 antibody titres.

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