New Guidelines developed for HER2 testing in gastroesophagea
The panel proposed 11 recommendations, with strong consensus. These include recommendations that tumor specimens from all patients with advanced GEA be assessed for HER2 status before HER2-targeted therapy initiation. Combination chemotherapy and a HER2-targeted agent should be offered as initial therapy for all patients with HER2-positive advanced GEA. Guidelines are provided for pathologists for morphologic selection of neoplastic tissue, testing algorithms, scoring methods, interpretation and reporting of results, and laboratory quality assurance...