New PET imaging technique may help monitor neurological dise
Olfactory neurons in the nasal cavity are the primary source of our sense of smell. Unlike many types of neurons, olfactory neurons are continuously generated throughout the adult lifespan. This uniquely high rate of neuronal birth and death makes olfactory neurons particularly sensitive to the detrimental effects of progressive neurodevelopmental and neurodegenerative disease.

In work published this week in the JCI, a team led by Jacob Hooker at Harvard Medical School assessed GV1-57, a radiotracer that specifically binds to mature olfactory sensory neurons, as an approach for quantifying neuronal populations with PET imaging. Using GV1-57, they were able to detect neuron generation during rodent postnatal development as well as neuron degeneration in rodent models of aging and neurodegenerative disease.


Read more at: https://medicalxpress.com/news/2017-01-pet-imaging-technique-neurological-disease.html#jCp
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