New, more infectious strain of COVID-19 now dominates global
Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...Now open: Certificate Course in Management of Covid-19 by Govt. Of Gujarat and PlexusMDKnow more...
Get authentic, real-time news that helps you fight COVID-19 better.
Install PlexusMD App for doctors. It's free.
Researchers have shown that a variation in the viral genome of COVID-19 improved its ability to infect human cells and helped it become the dominant strain circulating around the world today. Laboratory experiments have, meanwhile, shown that the variant is three to six times more capable of infecting human cells.

The study, published today in the journal Cell, shows the variation is more infectious in cell cultures under laboratory conditions. The variant, named 'D614G', makes a small but effective change in the 'spike' glycoprotein that protrudes from the surface of the virus, which it uses to enter and infect human cells.

The D614G variant of COVID-19 quickly took over as the dominant strain soon after it first appeared, with geographic samples showing a significant shift in viral population from the original, to the new strain of the virus.

The full peer-reviewed study published today confirms this, and also that the new D614G genome mutation variant is also more infectious under laboratory conditions.

Data provided by the team in Sheffield suggested that the new strain was associated with higher viral loads in the upper respiratory tract of patients with COVID-19, meaning the virus's ability to infect people could be increased.

"Fortunately at this stage, it does not seem that viruses with D614G cause more severe disease," said researchers.

Source: https://www.cell.com/cell/fulltext/S0092-8674(20)30820-5
H●●●l S●●h and 14 others like this26 shares
Like
Comment
Share
Dr. S●●●●●m S●●●●y P●●●●●l
Dr. S●●●●●m S●●●●y P●●●●●l General Medicine
Interesting read !
Jul 5, 2020Like