Nightmare cases: The artificial iris
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According to the American Academy of Ophthalmology cosmetic iris implants are non-FDA-approved procedures that can result in severe, potentially blinding complications. Patients who undergo the cosmetic procedure can experience increased IOP, cataracts, injury to the cornea, or reduced vision or blindness,

A female patient aged 20 years who had main complaints of dimness of vision associated with pain and redness in both eyes. She had undergone cosmetic lens implantation 2 years back, as she had wanted to change the color of her eyes. Post-lens implantation, the patient was asymptomatic for 6 months but slowly developed raised IOP of 40 mm Hg and 30 mm Hg for the right and left eyes, respectively. The cosmetic lenses were removed by the referring surgeon from both eyes, but her symptoms failed to subside. The patient presented with cataract, endothelial decompensation, raised IOP and irregular iris architecture with patches of atrophy (Figures 1 and 2). The persistently dilated pupil failed to constrict even after lowering the IOP with medications. This was probably due to mechanical trauma induced by the iris implant and sphincter damage due to raised IOP. The patient was on topical anti-glaucoma drugs and nonsteroidal anti-inflammatory drops.

Specular microscopy was performed. The preoperative specular count could not be assessed for the right eye, whereas the endothelial cell count for the left eye was 1,750 cells/mm2. The right eye underwent phacoemulsification with single-pass four-throw pupilloplasty and pre-Descemet’s endothelial keratoplasty as a single-stage procedure. The left eye underwent phacoemulsification with pupilloplasty. PDEK was not considered initially for the case, but eventually the left eye also underwent endothelial decompensation, and PDEK was performed 6 months after the initial surgery.

Postoperatively, there was a dramatic improvement in the visual acuity and raised IOP. The preoperative best corrected visual acuity improved from 20/800 and 20/400 on Snellen’s chart to 20/20 in both eyes at 3 months’ follow-up and persisted thereafter. At 1-month follow-up, there were no signs of active inflammation with deep anterior chambers. The postoperative IOP in both eyes was recorded to be 17 mm Hg and 15 mm Hg in the right eye and left eye, respectively. Intraoperatively, difficulty was observed while performing pupilloplasty due to thin, friable iris tissue that gaped during the procedure. However, gentle handling of the iris tissue, along with a second attempt at the procedure, facilitated the completion of the procedure. No other major complications such as graft detachment or failure were observed. Currently, the patient is on no topical medication

In conclusion, cosmetic iris implants have not been evaluated. When complications occur, the implants often must be removed via additional surgery, which carries its own risks of damaging the eye.



Source: https://www.healio.com/ophthalmology/retina-vitreous/news/online/{fadfeb16-aded-4ce6-9432-9fe763f52d27}/nightmare-cases-the-artificial-iris
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