OCT-Angiography Findings Before and After Vitrectomy for Mac
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To investigate the vascular remodeling of optical coherence tomography (OCT)-angiography (OCTA) in full-thickness macular hole (FTMH) surgery.

This retrospective, observational case series included 33 eyes of 33 patients with full-thickness macular holes who underwent epiretinal membrane removal. Data were collected on best-corrected visual acuity, structural B-scan optical coherence tomography, and OCTA preoperatively and at 1, 3, and 6 months postoperatively. OCTA was used to assess the retinal vascular density of the superficial vascular plexus and deep vascular plexus. Vascular density was assessed using the early treatment of diabetic retinopathy study grid for the whole, inner, and outer grids.

A statistically significant correlation was found between the VD (whole, inner, and outer grids) of the superficial vascular plexus only from baseline to 1 month postoperatively. Similarly, vascular density was correlated from baseline to 1, 3, and 6 months postoperatively to the whole, inner, and outer early treatment of diabetic retinopathy study grids of deep vascular plexus. Best-corrected visual acuity and vascular density were significantly correlated with superficial vascular plexus and DVP at baseline and 6 months. The most significant correlation was observed at 6 months between best-corrected visual acuity and deep vascular plexus in the whole, inner, and outer early treatment of diabetic retinopathy study grids.

Superficial vascular plexus and deep vascular plexus are affected by full-thickness macular hole, with the most significant effects being on the deep vascular plexus. full-thickness macular hole surgery leads to an improvement in the best-corrected visual acuity in many eyes and the restoration of the vascular density, especially of the deep vascular plexus.

Source:https://journals.lww.com/retinajournal/Abstract/9000/OCT_Angiography_Findings_Before_and_After.95660.aspx
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