Obesity associated with increased odds of acute renal failur
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Adults with obesity who died of COVID-19 in Italy were more likely to experience nonrespiratory complications such as acute renal failure and shock than those without obesity, with higher odds for those younger than 60 years, according to study data.

This study aimed to assess the impact of obesity on nonrespiratory complications in patients dying with COVID-19.

Medical charts of 3,694 of patients dying with COVID-19 in Italy were reviewed to extract information on demographics, preexisting comorbidities, and in-hospital complications leading to death. Multivariate logistic regressions were performed to assess the association of obesity with nonrespiratory complications.

Results:
-- Obesity was present in 411/3,694 (11.1%) patients dying with COVID-19.

-- Obesity was significantly associated with increased probability of experiencing acute renal failure and shock.

-- The associations of obesity with acute renal failure and shock were stronger in patients aged less than 60 years than in those aged 60 years or older.

Conclusively, in patients dying with COVID-19 in Italy, obesity is associated with an increased probability of nonrespiratory complications, particularly shock and acute renal failure. These associations seem stronger in younger than in older adults. Strategies should be put in place in patients with COVID-19 with obesity to prevent these complications.

Source: https://onlinelibrary.wiley.com/doi/full/10.1002/oby.23007?campaign=wolearlyview
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