Ocular TB in a patient with membranous nephropathy
Membranous nephropathy (MN), a chronic kidney disease (CKD), due to hypoproteinemia, malnutrition, anemia, long-term intake of immunosuppressive agents, changes in cellular immune state, and decrease in antimicrobial peptides, is a high risk for Mycobacterium tuberculosis (MTB) infection, which can cause tuberculosis (TB).

TB manifests by various clinical symptoms. Ocular symptoms is a rare presentation of TB. Published in Medicine, the authors describe a case of ocular tuberculosis in a patient with MN.

A 63-year-old man with membranous nephropathy (MN) history presented with ocular symptoms. According to the pathological manifestations of ocular tissue biopsy and a positive polymerase chain reaction (PCR) on samples from sputum and bronchoalveolar lavage fluid (BALF), a diagnosis of disseminated tuberculosis was elicited.

Major takeaway:-
Clinicians should be aware of the possibility of TB in cases of immunocompromised patients and perform an appropriate diagnostic work-up for TB.