One Third Of Patients Hospitalized With COVID-19 Have Lung C
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A new study has shown that most patients discharged from hospital after experiencing severe COVID-19 infection appear to return to full health, although up to a third do still have evidence of effects upon the lungs one year on. People are most commonly hospitalised for COVID-19 infection when it affects the lungs -- termed COVID-19 pneumonia.

Whilst significant progress has been made in understanding and treating acute COVID-19 pneumonia, very little is understood about how long it takes for patients to fully recover and whether changes within the lungs persist. In this new study, researchers investigated the natural history of recovery from severe COVID-19 pneumonia up to one year after hospitalisation.

83 patients were recruited after they were discharged from hospital following severe COVID-19 pneumonia and were followed up after three, six, nine and twelve months. At each time point they underwent clinical assessment as well as measures of how well the lungs function, a CT scan of their chest to take a picture of the lungs, and a walking test.

Over 12 months in most patients there was an improvement in symptoms, exercise capacity, and COVID-19 related CT changes. By 12 months the majority of patients appeared to have fully recovered although about 5% of patients still reported breathlessness. A third of patients' measures of lung function were still reduced -- in particular how efficiently oxygen is transferred in the lungs into the blood -- and this was more frequently found in women than in men.

In around a quarter of patients CT scans showed there were still small areas of change in the lungs, and this was more common in patients with more severe lung changes at time of hospitalisation. A researcher said, "the majority of patients with severe COVID-19 pneumonia appeared to fully recover, although for some patients this took many months. Women were more likely to have persistent reductions in lung function tests and further investigation is needed to understand if there is a sex specific difference in how patient's recover.

Source:
https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(21)00174-0/fulltext
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