A one-in-the-world genetic mutation is responsible for Egyptian woman Eman Ahmed's weight. Results of Eman's gene study analyzing 91 different types of genes related to obesity, found that she has a mutation in the LEPR gene (the c.1055G>A, p.(Cys352Tyr) variant). She has another genetic mutation, but it isn't contributing to her obesity. The gene controls hormone leptin which is better known as the 'satiety hormone'. Because of the leptin receptor deficiency from early life, Eman's brain has perceived that she is constantly starving. That has led her to constantly seek food, store it avidly in her body as fat and conserve energy.