Only One In Four People Experience Mild Side Effects From Co
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One in four people experiences mild, short-lived systemic side effects after receiving either the Pfizer or AstraZeneca vaccine, with headache, fatigue, and tenderness the most common symptoms, suggest the findings of a new study. Most side effects peaked within the first 24 hours following vaccination and usually lasted 1-2 days.

The study also reports a significant decrease of infection rates from 12 to 21 days after the first dose of the Pfizer (58% reduction) and AstraZeneca (39% reduction) vaccines compared to a control group. The drop in infection at least 21 days after the first dose for Pfizer is 69% and for AstraZeneca 60%.

The data comes from 627,383 users of the ZOE COVID Symptom Study app who self-reported systemic and local effects within eight days of receiving one or two doses of the Pfizer vaccine or one dose of the AstraZeneca vaccine between December 8 and March 10.

-25.4 percent of vaccinated people indicated suffering from one or more systemic side effects, whereas 66.2 percent reported one or more local side effects.

-13.5 percent of participants reported side effects after their first Pfizer dose, 22.0 percent after the second Pfizer dose, and 33.7 percent after the first AstraZeneca dose.

-The most-reported systemic side effect was a headache. 7.8 percent of people reported suffering from headaches after the first Pfizer dose and 13.2 percent after the second Pfizer dose. 22.8 percent of people who had the first dose of the AstraZeneca vaccine reported a headache.

-The second most reported systemic side effect was fatigue. 8.4% and 14.4% of participants reported fatigue after first and second dose of Pfizer vaccine and 21.1% reported fatigue after their first dose of AstraZeneca vaccine.

The most common local side effect was tenderness: 57.2 percent and 50.9 percent after the first and second dose of Pfizer vaccine, and 49.3% after the first dose of AstraZeneca vaccine. Importantly, this research identifies that side effects were more common among people under 55 years of age and among women.

Also, participants who had a confirmed case of prior COVID-19 were three times more likely to have side effects that affect the whole body after receiving doses of the Pfizer vaccine than those without known infection and almost twice more likely after the first dose of the AstraZeneca vaccine.

Source:
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00224-3/fulltext
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