Orbital cellular blue nevus complicated by malignant melanom
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Melanocytic lesions encompass a spectrum of disorders ranging from benign lesions to malignant pathology. The cellular blue nevus (CBN) represents a particularly rare entity that can occur in the periocular area. Although these lesions are considered to represent benign proliferation of deeply located melanocytes that have failed migration to the epithelium, concern has been raised regarding the malignant transformation of atypical CBN. The ability to predict this change with subsequent locally aggressive behavior and potential distant metastasis is a controversial and unresolved issue. We present a patient with an initially slowly progressive orbital CBN over 40 years, culminating in malignant transformation.

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