Osseous metaplasia and Mature Bone Formation in a Follicular
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Cases of multinodular goitre, thyroid hyperplasia, follicular adenoma, papillary thyroid carcinoma and anaplastic thyroid carcinoma have been reported with histopathologic findings of osseous metaplasia (OM), bone marrow metaplasia (BMM), ectopic bone formation (EBF), ossification, and extramedullary hematopoiesis (EMH). To date, no report of a follicular adenoma with OM and mature EBF in the absence of EMH has been reported in the English language.63-year-old woman with an incidental finding of thyroid nodule unable to be biopsied. One area was found to contain OM with mature EBF and without vascular invasion. The surrounding tissue was unremarkable, and no malignancy was found.Ectopic bone formation and osseous metaplasia in a thyroid nodule has an extensive differential diagnosis, from thyroid related pathologies to parathyroid causes, congenital syndromes and hamartoma....

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